Toward Development of Psychosocial Measures for Automated Insulin Delivery

Automated insulin delivery for t ype 1 diabetes Garry

Purpose of review Automated insulin delivery using the subcutaneous site for both glucose sensing and insulin delivery, while not commercially available, is starting to be implemented in the research environment. Here, we review issues with glucose sensing and insulin delivery algorithms that need to be resolved in order to achieve a closed-loop system. Recent findings Glucose sensing technolog...

Psychosocial measures.

Update on mathematical modeling research to support the development of automated insulin delivery systems.

One year after its initial meeting, the Glycemia Modeling Working Group reconvened during the 2009 Diabetes Technology Meeting in San Francisco, CA. The discussion, involving 39 scientists, again focused on the need for individual investigators to have access to the clinical data required to develop and refine models of glucose metabolism, the need to understand the differences among the distin...

Mathematical modeling research to support the development of automated insulin-delivery systems.

The world leaders in glycemia modeling convened during the Eighth Annual Diabetes Technology Meeting in Bethesda, Maryland, on 14 November 2008, to discuss the current practices in mathematical modeling and make recommendations for its use in developing automated insulin-delivery systems. This report summarizes the collective views of the 25 participating experts in addressing the following fou...

Development and Evaluation of Microemulsions for Transdermal Delivery of Insulin

Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. The pseudoternary phase diagrams were constructed to determine the composition of microemulsions. The insulin permeation flux of microemulsions containing oleic acid as oil phase through excised mou...